ADAMTS1, MPDZ, MVD, and SEZ6: candidate genes for autosomal recessive nonsyndromic hearing impairment.

doi:10.1038/s41431-021-00913-x

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Article

ADAMTS1, MPDZ, MVD, and SEZ6: candidate genes for autosomal recessive nonsyndromic hearing impairment.

European journal of human genetics : EJHG - 1 Jan 2022

Bharadwaj Thashi, Schrauwen Isabelle, Rehman Sakina, Liaqat Khurram, Acharya Anushree, Giese Arnaud P J, Nouel-Saied Liz M, Nasir Abdul, Everard Jenna L, Pollock Lana M, Zhu Shaoyuan, Bamshad Michael J, Nickerson Deborah A, Ali Raja Hussain, Ullah Asmat, Wali Abdul, Ali Ghazanfar, Santos-Cortez Regie Lyn P, Ahmed Zubair M, McDermott Brian M, Ansar Muhammad, Riazuddin Saima, Ahmad Wasim, Leal Suzanne M

Abstract excerpt

Hearing impairment (HI) is a common disorder of sensorineural function with a highly heterogeneous genetic background. Although substantial progress has been made in the understanding of the genetic etiology of hereditary HI, many genes implicated in HI remain undiscovered. Via exome and Sanger sequencing of DNA samples obtained from consanguineous Pakistani families that segregate profound prelingual...

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PMID: 34135477
DOI: 10.1038/s41431-021-00913-x
PMCID: PMC8738740

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