Integrating gut microbiome and host immune markers to understand the pathogenesis of Clostridioides difficile infection

Abstract excerpt

Clostridioides difficile (C. difficile) infection is the most common cause of healthcare–associated infection and an important cause of morbidity and mortality among hospitalized patients. A comprehensive understanding of C. difficile infection (CDI) pathogenesis is crucial for disease diagnosis, treatment, and prevention. Here, we characterized gut microbial compositions and a broad panel of innate and adaptive...

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