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Article

What happens after menopause? (WHAM): A prospective controlled study of sleep quality up to 12 months after premenopausal risk-reducing salpingo-oophorectomy.

Gynecologic oncology - 1 Aug 2021

Hickey Martha, Moss Katrina M, Krejany Efrosinia O, Wrede C David, Domchek Susan M, Kirk Judy, Brand Alison, Trainer Alison, Mishra Gita D, Baker Fiona C

Abstract excerpt

OBJECTIVE: Sleep difficulties impair function and increase the risk of depression at menopause and premenopausal oophorectomy may further worsen sleep. However, prospective data are limited, and it remains uncertain whether Hormone Therapy (HT) improves sleep. This prospective observational study measured sleep quality before and up to 12 months after risk-reducing salpingo-oophorectomy (RRSO) compared to a...

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Source

Identifiers

PMID: 34116835
DOI: 10.1016/j.ygyno.2021.05.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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