Gene Therapy for Overactive Bladder: A Review of BK-Channel α-Subunit Gene Transfer

doi:10.2147/tcrm.s291798

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Gene Therapy for Overactive Bladder: A Review of BK-Channel α-Subunit Gene Transfer

1 Jun 2021

Abstract excerpt

A need exists for local (ie, bladder-specific) interventions to treat overactive bladder (OAB) with low risk of unwanted postprocedural outcomes. Gene therapy targeted to leverage endogenous physiology in bladder cells may assist in restoring normal cell and organ function. Herein, we review the potential promise of gene therapy for treating OAB, focusing on gene transfer of URO-902, a non-viral naked plasmid DNA...

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PMID: 34113116
DOI: 10.2147/tcrm.s291798

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