Article
Co-expression of low-risk HPV E6/E7 and EBV LMP-1 leads to precancerous lesions by DNA damage.
BMC cancer - 10 Jun 2021
Uehara Karina, Tanabe Yasuka, Hirota Shintaro, Higa Saki, Toyoda Zensei, Kurima Kiyoto, Kina Shinichiro, Nakasone Toshiyuki, Arasaki Akira, Kinjo Takao
Abstract excerpt
BACKGROUND: Low-risk human papillomavirus (HPV), such as types 6 and 11, is considered non-oncogenic, but these types have been detected in oral cancer tissue samples, suggesting their possible involvement in oral carcinogenesis. Because double infection of high-risk HPV and Epstein-Barr virus (EBV) is known to be involved in oral carcinogenesis, we hypothesized that low-risk HPV and EBV co-infection can...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.