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Article

Genome-Wide Association Study Identifies Genetic Risk Factors for Spastic Cerebral Palsy.

Neurosurgery - 16 Aug 2021

Hale Andrew T, Akinnusotu Oluwatoyin, He Jing, Wang Janey, Hibshman Natalie, Shannon Chevis N, Naftel Robert P

Abstract excerpt

BACKGROUND: Although many clinical risk factors of spastic cerebral palsy (CP) have been identified, the genetic basis of spastic CP is largely unknown. Here, using whole-genome genetic information linked to a deidentified electronic health record (BioVU) with replication in the UK Biobank and FinnGen, we perform the first genome-wide association study (GWAS) for spastic CP. OBJECTIVE: To define the genetic basis...

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Source

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Identifiers

PMID: 34098570
DOI: 10.1093/neuros/nyab184
PMCID: PMC8364821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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