Article
Durvalumab consolidation therapy in a patient with stage IIIB unresectable NSCLC harboring a MET exon 14 splice site alteration.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2021
Cytryn Samuel, Ferreira Virginia, Boland Patrick, Chachoua Abraham, Sabari Joshua
Abstract excerpt
BACKGROUND: Recent literature has identified significant benefit of consolidation durvalumab following chemoradiotherapy in patients with unresectable non-small cell lung cancer (NSCLC). However, immunotherapy has demonstrated modest benefit in patients harboring oncogene driver mutations. While standard of care in metastatic oncogenic driven tumors is targeted tyrosine kinase inhibitors (TKIs), there is little...
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