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Article

Single-nucleotide conservation state annotation of the SARS-CoV-2 genome.

Communications biology - 3 Jun 2021

Kwon Soo Bin, Ernst Jason

Abstract excerpt

Given the global impact and severity of COVID-19, there is a pressing need for a better understanding of the SARS-CoV-2 genome and mutations. Multi-strain sequence alignments of coronaviruses (CoV) provide important information for interpreting the genome and its variation. We apply a comparative genomics method, ConsHMM, to the multi-strain alignments of CoV to annotate every base of the SARS-CoV-2 genome with...

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Identifiers

PMID: 34083758
DOI: 10.1038/s42003-021-02231-w
PMCID: PMC8175581

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