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Article

Molecular analysis of the AGXT gene in Syrian patients suspected with primary hyperoxaluria type 1.

BMC medical genomics - 3 Jun 2021

Murad Hossam, Alhalabi Mohamad Baseel, Dabboul Amir, Alfakseh Nour, Nweder Mohamad Sayah, Zghib Youssef, Wannous Hala

Abstract excerpt

BACKGROUND: Characterization of the molecular basis of primary hyperoxaluria type 1 (PH-1) in Syria has been accomplished through the analysis of 90 unrelated chromosomes from 45 Syrians patients with PH-1 from different regions. METHODS: Alanine glyoxylate aminotransferase (AGXT) gene mutations have been analyzed by using molecular detection methods based on the direct DNA sequencing for all exons of the AGXT...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34082749
DOI: 10.1186/s12920-021-00996-x
PMCID: PMC8176596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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