Article
[Targeted therapies for non-small cell lung cancer : state of the art in 2021].
Revue medicale de Liege - 1 May 2021
Sibille A, Corhay J L, Vaillant F, Paulus A, Louis R, Duysinx B
Abstract excerpt
The majority of non-small cell lung cancers are diagnosed as advanced disease. Subsets of adenocarcinomas and of squamous cell carcinomas in nonsmokers present a molecular aberration leading to tumour survival. Epidermal Growth Factor Receptor (EGFR), Anaplastic Lymphoma Kinase (ALK) and Repressor Of Silencing1 (ROS1) have been identified and targeted with good efficacy for fifteen years. Newer inhibitors brought...
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