Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunological and hematological outcomes following protracted low dose/low dose rate ionizing radiation and simulated microgravity

1 Jun 2021

Abstract excerpt

Using a ground-based model to simulate spaceflight [21-days of single-housed, hindlimb unloading (HLU) combined with continuous low-dose gamma irradiation (LDR, total dose of 0.04 Gy)], an in-depth survey of the immune and hematological systems of mice at 7-days post-exposure was performed. Collected blood was profiled with a hematology analyzer and spleens were analyzed by whole transcriptome shotgun sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Climate Change and Health Impacts
Share to High Altitude and Hypoxia
Share to Spaceflight effects on biology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34075076
DOI: 10.1038/s41598-021-90439-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunological and hematological outcomes following protracted low dose/low dose rate ionizing radiation and simulated microgravityPMID 34075076Read ↗

Using single-sample networks to identify the contrasting patterns of gene interactions and reveal the radiation dose-dependent effects in multiple tissues of spaceflight miceSemantic proximity Read ↗

Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological SequelaeSemantic proximity Read ↗

Age and Sex Divergence in Hematopoietic Radiosensitivity in Aged Mouse Models of the Hematopoietic Acute Radiation SyndromeSemantic proximity Read ↗

Accelerated Hematopoietic Stem Cell Aging in SpaceSemantic proximity Read ↗

Lifelong Residual bone Marrow Damage in Murine Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS): A Compilation of Studies Comprising the Indiana University ExperienceSemantic proximity Read ↗

Effect of Age at Time of Irradiation, Sex, Genetic Diversity, and Granulopoietic Cytokine Radiomitigation on Lifespan and Lymphoma Development in Murine H-ARS Survivors.Semantic proximity Read ↗

Plasma miRNA as Biomarkers for Assessment of Total-Body Radiation Exposure DosimetrySemantic proximity Read ↗

Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflightSemantic proximity Read ↗

Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflightSemantic proximity Read ↗

Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled MicrogravitySemantic proximity Read ↗

Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolomeSemantic proximity Read ↗

Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaquesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.