Article
Deglycosylated Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1 Signaling Pathway.
Molecules (Basel, Switzerland) - 10 May 2021
Ruan Hao, Gao Shaoyan, Li Shuangling, Luan Jiaoyan, Jiang Qiuyan, Li Xiaohe, Yin Huijun, Zhou Honggang, Yang Cheng
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening lung disease characterized by the proliferation of myofibroblasts and deposition of extracellular matrix that results in irreversible distortion of the lung structure and the formation of focal fibrosis. The molecular mechanism of IPF is not fully understood, and there is no satisfactory treatment. However, most studies suggest that abnormal...
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