Article
Akt Kinase Intervenes in Flavivirus Replication by Interacting with Viral Protein NS5.
Viruses - 12 May 2021
Albentosa-González Laura, Jimenez de Oya Nereida, Arias Armando, Clemente-Casares Pilar, Martin-Acebes Miguel Ángel, Saiz Juan Carlos, Sabariegos Rosario, Mas Antonio
Abstract excerpt
Arthropod-borne flaviviruses, such as Zika virus (ZIKV), Usutu virus (USUV), and West Nile virus (WNV), are a growing cause of human illness and death around the world. Presently, no licensed antivirals to control them are available and, therefore, search for broad-spectrum antivirals, including host-directed compounds, is essential. The PI3K/Akt pathway controls essential cellular functions involved in cell...
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