Article
Mvda is required for zebrafish early development.
Biological research - 29 May 2021
Wong Wenghong, Huang Yike, Wu Zhuanbin, Kong Yu, Luan Jing, Zhang Qiaoan, Pan Jiewen, Yan Kexiang, Zhang Zhenghua
Abstract excerpt
BACKGROUND: The MVD gene mutations are identified in porokeratosis, which is considered a skin-specific autoinflammatory keratinization disease. However, the biological function of MVD gene remains largely unknown. Therefore, we analyzed the function of mvda gene, orthologous to the human MVD gene, in developing zebrafish. METHODS: Morpholino antisense oligonucleotide technique was used to generate mvda...
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