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Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

28 May 2021

Abstract excerpt

Immunotherapy has reshaped the field of cancer therapeutics but the population that benefits are small in many tumor types, warranting a companion diagnostic test. While immunohistochemistry (IHC) for programmed death-ligand 1 (PD-L1) or mismatch repair (MMR) and polymerase chain reaction (PCR) for microsatellite instability (MSI) are the only approved companion diagnostics others are under consideration. An...

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PMID: 34050252
DOI: 10.1038/s41698-021-00184-1

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