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Article

RegAB Homolog of Burkholderia pseudomallei is the Master Regulator of Redox Control and involved in Virulence.

PLoS pathogens - 1 May 2021

Phenn Julia, Pané-Farré Jan, Meukow Nikolai, Klein Annelie, Troitzsch Anne, Tan Patrick, Fuchs Stephan, Wagner Gabriel E, Lichtenegger Sabine, Steinmetz Ivo, Kohler Christian

Abstract excerpt

Burkholderia pseudomallei, the etiological agent of melioidosis in humans and animals, often occupies environmental niches and infection sites characterized by limited concentrations of oxygen. Versatile genomic features enable this pathogen to maintain its physiology and virulence under hypoxia, but the crucial regulatory networks employed to switch from oxygen dependent respiration to alternative terminal...

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Identifiers

PMID: 34048488
DOI: 10.1371/journal.ppat.1009604
PMCID: PMC8191878

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