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Article

In silico analysis of human herpes virus-8 genome: a comparison of the K1, VR1, and VR2 regions for genotyping and global geographical distribution.

Scientific reports - 2 Jan 2025

Khodadad Nastaran, Hashempour Ava, Akbarinia Shokufeh

Abstract excerpt

Investigations of the K1 gene revealed six main genotypes clustered according to geography. Here, the global distribution and HHV8 genotyping using the K1 gene and two hypervariable regions (VR1 and VR2) were evaluated. We searched GenBank for 6,889 HHV8-K1 genes via various keywords, selecting sequences longer than 730 bp. Afterwards, the VR1 and VR2 regions were derived from the K1 genes, and genotyping of the...

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Identifiers

PMID: 39747627
DOI: 10.1038/s41598-024-84376-2
PMCID: PMC11696107

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