Calculation of the Paternity Index for STR with tri-allelic patterns in paternity testing.

doi:10.1016/j.forsciint.2021.110832

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Article

Calculation of the Paternity Index for STR with tri-allelic patterns in paternity testing.

Forensic science international - 1 Jul 2021

Yang Qinrui, Yao Yining, Shao Chengchen, Zhou Yuxiang, Li Hui, Li Chengtao, Tang Qiqun, Xie Jianhui

Abstract excerpt

The calculation of the paternity index (PI) value of common bi-allelic genotypes at STR loci has been standardized in paternity cases. However, for tri-allelic patterns, a rare category of genotyping aberration in forensic practice, the statistical analysis in paternity testing remains disputed. The Type 1 tri-allelic pattern generally results from somatic mutation in the early stage of individual development....

Topics

Alleles
Humans
Likelihood Functions
Male
Microsatellite Repeats
Models, Statistical
Paternity
Segmental Duplications, Genomic

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PMID: 34034205
DOI: 10.1016/j.forsciint.2021.110832

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