Article
[A new method for calculating the paternity index in presence of mutation].
Fa yi xue za zhi - 1 Jun 2009
Lü De-Jian, Lu Hui-Ling
Abstract excerpt
OBJECTIVE: To introduce a method of calculating the paternity index (PI) for autosomal codominant markers when the mutation is encountered. METHODS: Assuming mutation arises with a mutational probability before an allele segregates and transmits to child with 1/2 chance, the probability of a random man giving an allele to child is the allele frequency in population. Considering only one mutation event in one...
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