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Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism

24 May 2021

Abstract excerpt

OBJECTIVE: To evaluate the taxonomic composition of the gut microbiome in gout patients with and without tophi formation, and predict bacterial functions that might have an impact on urate metabolism. METHODS: Hypervariable V3-V4 regions of the bacterial 16S rRNA gene from fecal samples of gout patients with and without tophi (n = 33 and n = 25, respectively) were sequenced and compared to fecal samples from 53...

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Share to Gout, Hyperuricemia, Uric Acid
Share to Gut microbiota and health
Share to Urinary Tract Infections Management

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PMID: 34030623
DOI: 10.1186/s10020-021-00311-5

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