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Clinical validity and utility of preconception expanded carrier screening for the management of reproductive genetic risk in IVF and general population

23 Mar 2021

Abstract excerpt

STUDY QUESTION: What is the clinical validity and utility of preconception Expanded Carrier Screening (ECS) application on the management of prospective parents? SUMMARY ANSWER: The high detection rate of at-risk couples (ARCs) and the high proportion opting for IVF/preimplantation genetic testing (PGT) treatment demonstrate the clinical utility of ECS in the preconception space in IVF and general population....

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PMID: 34021342
DOI: 10.1093/humrep/deab087

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