Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deciphering balanced translocations in infertile males by next-generation sequencing to identify candidate genes for spermatogenesis disorders.

Molecular human reproduction - 29 May 2021

Yammine T, Reynaud N, Lejeune H, Diguet F, Rollat-Farnier P A, Labalme A, Plotton I, Farra C, Sanlaville D, Chouery E, Schluth-Bolard C

Abstract excerpt

Male infertility affects about 7% of the general male population. Balanced structural chromosomal rearrangements are observed in 0.4-1.4% of infertile males and are considered as a well-established cause of infertility. However, underlying pathophysiological mechanisms still need to be clarified. A strategy combining standard and high throughput cytogenetic and molecular technologies was applied in order to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthenozoospermia
Share to Axonemal Dyneins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Lactamases

Share to Chromosome Breakpoints

Share to Infertility, Male

Share to Phosphoprotein Phosphatases

Share to Spermatogenesis

Share to Translocation, Genetic

Source

Identifiers

PMID: 34009290
DOI: 10.1093/molehr/gaab034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deciphering balanced translocations in infertile males by next-generation sequencing to identify candidate genes for spermatogenesis disorders.PMID 34009290Read ↗

Investigation of the genetic etiology in male infertility with apparently balanced chromosomal structural rearrangements by genome sequencingSemantic proximity Read ↗

Copy number variations in spermatogenic failure patients with chromosomal abnormalities and unexplained azoospermia.Semantic proximity Read ↗

Development of a novel next-generation sequencing panel for diagnosis of quantitative spermatogenic impairment.Semantic proximity Read ↗

Cryptic deletions are a common finding in "balanced" reciprocal and complex chromosome rearrangements: a study of 59 patients.Semantic proximity Read ↗

Male Infertility Diagnosis: Improvement of Genetic Analysis Performance by the Introduction of Pre-Diagnostic Genes in a Next-Generation Sequencing Custom-Made Panel.Semantic proximity Read ↗

The Role of Whole Exome Sequencing in the Genetic Evaluation of the Infertile Man.Semantic proximity Read ↗

Complex chromosomal rearrangements in infertile males: complexity of rearrangement affects spermatogenesisSemantic proximity Read ↗

Analysis of partial Y chromosome microdeletions and NGS data in Lithuanian infertile menSemantic proximity Read ↗

Exome sequencing and functional analyses revealedCETN1variants leads to impaired cell division and male fertilitySemantic proximity Read ↗

Cytogenetic Investigation of Infertile Patients in Hungary: A 10-Year Retrospective StudySemantic proximity Read ↗

A common 1.6 mb Y-chromosomal inversion predisposes to subsequent deletions and severe spermatogenic failure in humansSemantic proximity Read ↗

Next-generation sequencing: toward an increase in the diagnostic yield in patients with apparently idiopathic spermatogenic failure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.