Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling.

Analytical cellular pathology (Amsterdam) - 1 Jan 2021

Zhang Fan, Meng Jingfei, Jiang Hong, Feng Xing, Wei Dongshan, Meng Wen

Abstract excerpt

The expression of G2 and S phase-expressed-1 (GTSE1) was upregulated in human cancer. However, its expression and roles in lung cancer have not been identified yet. In our study, we reported that GTSE1 expression was statistically higher in lung tissues than in the adjacent noncancerous tissues which might be a consequence of hypomethylation of the GTSE1 promoter. The upregulated expression of GTSE1 mRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to A549 Cells
Share to Cell Movement
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Microtubule-Associated Proteins

Share to Proto-Oncogene Proteins c-akt

Share to RNA Interference

Share to TOR Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 34007784
DOI: 10.1155/2021/5589532
PMCID: PMC8110388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling.PMID 34007784Read ↗

GTSE1 is involved in breast cancer progression in p53 mutation-dependent mannerSemantic proximity Read ↗

SPAG1 Inhibits Cell Proliferation and Tumor Growth of Lung Adenocarcinoma via the AKT/mTORC1 Signaling AxisSemantic proximity Read ↗

GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver CancerSemantic proximity Read ↗

NUSAP1 knockdown inhibits cell growth and metastasis of non‐small‐cell lung cancer through regulating BTG2/PI3K/Akt signalingSemantic proximity Read ↗

Cancer-testis gene PIWIL1 promotes cell proliferation, migration, and invasion in lung adenocarcinoma.Semantic proximity Read ↗

Prognostic significance and molecular mechanisms of LPCAT1 in lung squamous cell carcinomaSemantic proximity Read ↗

LncRNA TP73-AS1 promoted the progression of lung adenocarcinoma via PI3K/AKT pathwaySemantic proximity Read ↗

High GTSE1 expression promotes cell proliferation, metastasis and cisplatin resistance in ccRCC and is associated with immune infiltrates and poor prognosisSemantic proximity Read ↗

YTHDF1 Facilitates Lung Adenocarcinoma Progression via Promotion of EEF1G Translation in a m6A-Dependent MannerSemantic proximity Read ↗

Hypoxia-mediated YTHDF2 expression and activation of the mTOR/AKT axis in lung squamous cell carcinomaSemantic proximity Read ↗

LpCat1 Promotes Malignant Transformation of Hepatocellular Carcinoma Cells by Directly Suppressing STAT1Semantic proximity Read ↗

GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.