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Article

Implementation of a next-generation sequencing-based targeted approach for full-length CYP3A4 gene sequencing.

Pharmacogenomics - 1 Jun 2021

Kivrane Agnija, Igumnova Viktorija, Kimsis Janis, Freimane Lauma, Sadovska Darja, Viksna Anda, Pole Ilva, Ranka Renate

Abstract excerpt

Aim: To evaluate the application of next-generation sequencing-based targeted protocol for full-length CYP3A4 gene sequencing analysis. Materials & methods: The developed sequencing protocol was applied to analyze human DNA samples (n = 7) obtained from tuberculosis patients admitted to the Riga East University Hospital, Center of Tuberculosis and Lung diseases. Results: The sequencing data quality was sufficient...

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Share to Cytochrome P-450 CYP3A
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PMID: 34003019
DOI: 10.2217/pgs-2020-0128

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