Article
Red hair is the null phenotype of MC1R.
Human mutation - 1 Aug 2008
Beaumont Kimberley A, Shekar Sri N, Cook Anthony L, Duffy David L, Sturm Richard A
Abstract excerpt
The Melanocortin-1 Receptor (MC1R) is a G-protein coupled receptor, which is responsible for production of the darker eumelanin pigment and the tanning response. The MC1R gene has many polymorphisms, some of which have been linked to variation in pigmentation phenotypes within human populations. In particular, the p.D84E, p.R151C, p.R160W and p.D294 H alleles have been strongly associated with red hair, fair skin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.