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100-My history of bornavirus infections hidden in vertebrate genomes

14 May 2021

Abstract excerpt

Although viruses have threatened our ancestors for millions of years, prehistoric epidemics of viruses are largely unknown. Endogenous bornavirus-like elements (EBLs) are ancient bornavirus sequences derived from the viral messenger RNAs that were reverse transcribed and inserted into animal genomes, most likely by retrotransposons. These elements can be used as molecular fossil records to trace past bornaviral...

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PMID: 33990470
DOI: 10.1073/pnas.2026235118

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