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Article

Elevated mature monocytes in bone marrow accompanied with a higher IPSS-R score predicts a poor prognosis in myelodysplastic syndromes.

BMC cancer - 13 May 2021

Wu An, Gao Panpan, Wu Ningning, Shi Cong, Huang Zhenya, Rong Chunmeng, Sun Ye, Sheng Lixia, Ouyang Guifang, Mu Qitian

Abstract excerpt

BACKGROUND: Myelodysplastic syndromes (MDS) is a group of heterogeneous myeloid clonal diseases originating from hematopoietic stem cells. Clinically, elevated mature monocyte in bone marrow is often observed, but its clinical value still remains unclear. METHODS: We retrospectively analyzed a cohort of 216 MDS patients to explore the prognostic value of the percentage of mature monocyte in bone marrow (PMMBM)....

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Identifiers

PMID: 33985456
DOI: 10.1186/s12885-021-08303-8
PMCID: PMC8117396

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