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Article

Loss of CEP70 function affects acrosome biogenesis and flagella formation during spermiogenesis.

Cell death & disease - 12 May 2021

Liu Qiang, Guo Qianying, Guo Wei, Song Shi, Wang Nan, Chen Xi, Sun Andi, Yan Liying, Qiao Jie

Abstract excerpt

The spermatogenesis process is complex and delicate, and any error in a step may cause spermatogenesis arrest and even male infertility. According to our previous transcriptomic data, CEP70 is highly expressed throughout various stages of human spermatogenesis, especially during the meiosis and deformation stages. CEP70 is present in sperm tails and that it exists in centrosomes as revealed by human centrosome...

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Identifiers

PMID: 33980814
DOI: 10.1038/s41419-021-03755-z
PMCID: PMC8116340

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