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Article

A non-coding indel polymorphism in the fruitless gene of Drosophila melanogaster exhibits antagonistically pleiotropic fitness effects.

Proceedings. Biological sciences - 12 May 2021

Jardine Michael D, Ruzicka Filip, Diffley Charlotte, Fowler Kevin, Reuter Max

Abstract excerpt

The amount of genetic variation for fitness within populations tends to exceed that expected under mutation-selection-drift balance. Several mechanisms have been proposed to actively maintain polymorphism and account for this discrepancy, including antagonistic pleiotropy (AP), where allelic variants have opposing effects on different components of fitness. Here, we identify a non-coding indel polymorphism in the...

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Identifiers

PMID: 33975471
DOI: 10.1098/rspb.2020.2958
PMCID: PMC8113896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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