Article
Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium.
Communications biology - 5 May 2021
Carter Lauren E, Cook David P, McCloskey Curtis W, Grondin Melanie A, Landry David A, Dang Tiffany, Collins Olga, Gamwell Lisa F, Dempster Holly A, Vanderhyden Barbara C
Abstract excerpt
The ovarian surface epithelium (OSE) is a monolayer of epithelial cells surrounding the ovary that ruptures during each ovulation to allow release of the oocyte. This wound is quickly repaired, but mechanisms promoting repair are poorly understood. The contribution of tissue-resident stem cells in the homeostasis of several epithelial tissues is widely accepted, but their involvement in OSE is unclear. We show...
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