Article
Phylogroup stability contrasts with high within sequence type complex dynamics of Escherichia coli bloodstream infection isolates over a 12-year period.
Genome medicine - 5 May 2021
Royer Guilhem, Darty Mélanie Mercier, Clermont Olivier, Condamine Bénédicte, Laouenan Cédric, Decousser Jean-Winoc, Vallenet David, Lefort Agnès, de Lastours Victoire, Denamur Erick
Abstract excerpt
BACKGROUND: Escherichia coli is the leading cause of bloodstream infections, associated with a significant mortality. Recent genomic analyses revealed that few clonal lineages are involved in bloodstream infections and captured the emergence of some of them. However, data on within sequence type (ST) population genetic structure evolution are rare. METHODS: We compared whole genome sequences of 912 E. coli...
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