Article
Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in mice
3 May 2021
Abstract excerpt
Abstract The consumption of energy-dense diets has contributed to an increase in the prevalence of obesity and its comorbidities worldwide. The adoption of unhealthy feeding habits often occurs at early age, prompting the early onset of metabolic disease with unknown consequences for reproductive function later in life. Recently, evidence has emerged regarding the intergenerational and transgenerational effects...
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