Article
Estimating Genetic Similarity Matrices Using Phylogenies.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jun 2021
Wang Shijia, Ge Shufei, Colijn Caroline, Biller Priscila, Wang Liangliang, Elliott Lloyd T
Abstract excerpt
Genetic similarity is a measure of the genetic relatedness among individuals. The standard method for computing these matrices involves the inner product of observed genetic variants. Such an approach is inaccurate or impossible if genotypes are not available, or not densely sampled, or of poor quality (e.g., genetic analysis of extinct species). We provide a new method for computing genetic similarities among...
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