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Article

The Cancer Stem Cell Niche in Ovarian Cancer and Its Impact on Immune Surveillance

15 Apr 2021

Abstract excerpt

Ovarian cancer is an aggressive gynaecological cancer with extremely poor prognosis, due to late diagnosis as well as the development of chemoresistance after first-line therapy. Research advances have found stem-like cells present in ovarian tumours, which exist in a dynamic niche and persist through therapy. The stem cell niche interacts extensively with the immune and non-immune components of the tumour...

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PMID: 33920983
DOI: 10.3390/ijms22084091

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