Article
HLA class I and II associations with common enteric pathogens in the first year of life.
EBioMedicine - 1 May 2021
McCowin Sayo E, Moreau G Brett, Haque Rashidul, Noble Janelle A, McDevitt Shana L, Donowitz Jeffrey R, Alam Md Masud, Kirkpatrick Beth D, Petri William A, Marie Chelsea
Abstract excerpt
BACKGROUND: genetic susceptibility to infection is mediated by numerous host factors, including the highly diverse, classical human leukocyte antigen (HLA) genes, which are critical genetic determinants of immunity. We systematically evaluated the effect of HLA alleles and haplotypes on susceptibility to 12 common enteric infections in children during the first year of life in an urban slum of Dhaka, Bangladesh....
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