Article
Serum uric acid and outcomes in patients with chronic heart failure through the whole spectrum of ejection fraction phenotypes: Analysis of the ESC-EORP Heart Failure Long-Term (HF LT) Registry.
European journal of internal medicine - 1 Jul 2021
Ambrosio Giuseppe, Leiro Marisa G Crespo, Lund Lars H, Coiro Stefano, Cardona Andrea, Filippatos Gerasimos, Ferrari Roberto, Piepoli Massimo F, Coats Andrew J S, Anker Stefan D, Laroche Cécile, Almenar-Bonet Luis, Poder Pentti, Valero David Bierge, Frisinghelli Anna, Maggioni Aldo P
Abstract excerpt
BACKGROUND: Retrospective analyses of clinical trials indicate that elevated serum uric acid (sUA) predicts poor outcome in heart failure (HF). Uric acid can contribute to inflammation and microvascular dysfunction, which may differently affect different left ventricular ejection fraction (LVEF) phenotypes. However, role of sUA across LVEF phenotypes is unknown. OBJECTIVES: We investigated sUA association with...
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