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Network-Based Analysis of Fatal Comorbidities of COVID-19 and Potential Therapeutics

23 Apr 2021

Abstract excerpt

COVID-19 is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The case-fatality rate is significantly higher in older patients and those with diabetes, cancer or cardiovascular disorders. The human proteins, angiotensin-converting enzyme 2 (ACE2), transmembrane protease serine 2 (TMPRSS2) and basigin (BSG), are involved in high-confidence host-pathogen...

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PMID: 33891554
DOI: 10.1109/tcbb.2021.3075299

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