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Biology of Polyomavirus miRNA

6 Apr 2021

Abstract excerpt

Polyomaviruses are a family of non-enveloped DNA viruses with wide host ranges. Human polyomaviruses typically cause asymptomatic infection and establish persistence but can be reactivated under certain conditions and cause severe diseases. Most well studied polyomaviruses encode a viral miRNA that regulates viral replication and pathogenesis by targeting both viral early genes and host genes. In this review, we...

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PMID: 33889147
DOI: 10.3389/fmicb.2021.662892

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