Article
Oxytocin system dysfunction in patients with treatment-resistant schizophrenia: Alterations of blood oxytocin levels and effect of a genetic variant of OXTR.
Journal of psychiatric research - 1 Jun 2021
Nakata Yusuke, Kanahara Nobuhisa, Kimura Atsushi, Niitsu Tomihisa, Komatsu Hideki, Oda Yasunori, Nakamura Miwako, Ishikawa Masatomo, Hasegawa Tadashi, Kamata Yu, Yamauchi Atsushi, Inazumi Kazuhiko, Kimura Hiroshi, Shiko Yuki, Kawasaki Yohei, Iyo Masaomi
Abstract excerpt
Treatment-resistant schizophrenia (TRS) has a quite complex pathophysiology that includes not only severe positive symptoms but also other symptom domains. Much attention has been devoted to the overlapping psychological and biological profiles of schizophrenia and autistic spectrum disorder (ASD). We compared TRS patients (n = 30) with schizophrenia patients in remission (RemSZ, n = 28) and ASD patients...
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