Article
Interplay between MAPK/ERK signaling pathway and MicroRNAs: A crucial mechanism regulating cancer cell metabolism and tumor progression.
Life sciences - 1 Aug 2021
Asl Elmira Roshani, Amini Mohammad, Najafi Souzan, Mansoori Behzad, Mokhtarzadeh Ahad, Mohammadi Ali, Lotfinejad Parisa, Bagheri Mehdi, Shirjang Solmaz, Lotfi Ziba, Rasmi Yousef, Baradaran Behzad
Abstract excerpt
Mitogen-activated protein kinase (MAPK) signal transduction, as a highly conserved signaling pathway, is reported to be involved in various biological events, including metabolic reprogramming, cell proliferation, survival, and differentiation. Mutations in key molecules involved in MAPK/ERK signaling and dysregulation of this pathway are very common events in various human malignancies, which make the MAPK...
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