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Article

Phenotyping the Spectrum of Traumatic Brain Injury: A Review and Pathway to Standardization.

Journal of neurotrauma - 1 Dec 2021

Pugh Mary Jo, Kennedy Eamonn, Prager Eric M, Humpherys Jeffrey, Dams-O'Connor Kristen, Hack Dallas, McCafferty Mary Katherine, Wolfe Jessica, Yaffe Kristine, McCrea Michael, Ferguson Adam R, Lancashire Lee, Ghajar Jamshid, Lumba-Brown Angela

Abstract excerpt

It is widely appreciated that the spectrum of traumatic brain injury (TBI), mild through severe, contains distinct clinical presentations, variably referred to as subtypes, phenotypes, and/or clinical profiles. As part of the Brain Trauma Blueprint TBI State of the Science, we review the current literature on TBI phenotyping with an emphasis on unsupervised methodological approaches, and describe five phenotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33858210
DOI: 10.1089/neu.2021.0059
PMCID: PMC8917880

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