Article
Proteogenomic Workflow Reveals Molecular Phenotypes Related to Breast Cancer Mammographic Appearance.
Journal of proteome research - 7 May 2021
De Marchi Tommaso, Pyl Paul Theodor, Sjöström Martin, Klasson Stina, Sartor Hanna, Tran Lena, Pekar Gyula, Malmström Johan, Malmström Lars, Niméus Emma
Abstract excerpt
Proteogenomic approaches have enabled the generat̲ion of novel information levels when compared to single omics studies although burdened by extensive experimental efforts. Here, we improved a data-independent acquisition mass spectrometry proteogenomic workflow to reveal distinct molecular features related to mammographic appearances in breast cancer. Our results reveal splicing processes detectable at the...
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