Article
Genomic diversity of multidrug-resistant Rhodococcus equi: novel sequence types, pangenome architecture, and phylogenomic evolution.
Applied and environmental microbiology - 22 Jul 2026
Lamichhane Bibek, Kabir Ajran, Adams Alexis A, Burns Logan, Johnson Beth, Sponseller Brett, Helmy Yosra A
Abstract excerpt
Rhodococcus equi is a major cause of life-threatening pneumonia in foals under 6 months of age and an opportunistic pathogen in immunocompromised humans. Although common in soil and equine farm environments, its evolutionary dynamics, virulence architecture, and pathways of antimicrobial resistance (AMR) emergence remain poorly understood. This study integrated phenotypic characterization and whole-genome...
Topics
- Rhodococcus equi
- Horses
- Animals
- Drug Resistance, Multiple, Bacterial
- Phylogeny
- Anti-Bacterial Agents
- Genome, Bacterial
- Genetic Variation
- Horse Diseases
- Actinomycetales Infections
- Whole Genome Sequencing
- Virulence
- Evolution, Molecular