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Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity

14 Apr 2021

Abstract excerpt

BACKGROUND: Coronavirus disease 2019 (COVID-19) caused by the enveloped RNA virus SARS-CoV-2 primarily affects the respiratory and gastrointestinal tracts. SARS-CoV-2 was isolated from fecal samples, and active viral replication was reported in human intestinal cells. The human gut also harbors an enormous amount of resident viruses (collectively known as the virome) that play a role in regulating host immunity...

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PMID: 33853691
DOI: 10.1186/s40168-021-01008-x

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