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Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences

16 Mar 2021

Abstract excerpt

STUDY QUESTION: Do embryos with different developmental competence exhibit different DNA methylation profiles at the blastocyst stage? SUMMARY ANSWER: We established genome-wide DNA methylome analysis for embryo trophectoderm (TE) biopsy samples and our findings demonstrated correlation of methylation profile of trophectoderm with euploidy status and with maternal age, indicating that genome-wide methylation...

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PMID: 33846747
DOI: 10.1093/humrep/deab074

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