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Article

Perifoveal Chorioretinal Atrophy after Subretinal Voretigene Neparvovec-rzyl for RPE65-Mediated Leber Congenital Amaurosis.

Ophthalmology. Retina - 1 Jan 2022

Gange William S, Sisk Robert A, Besirli Cagri G, Lee Thomas C, Havunjian Margaret, Schwartz Hillary, Borchert Mark, Sengillo Jesse D, Mendoza Carlos, Berrocal Audina M, Nagiel Aaron

Abstract excerpt

PURPOSE: To report an anatomic change following subretinal injection of voretigene neparvovec-rzyl (VN) for RPE65-mediated Leber congenital amaurosis. DESIGN: Multicenter, retrospective chart review. PARTICIPANTS: Patients who underwent subretinal VN injection at each of 4 participating institutions. METHODS: Patients were identified as having perifoveal chorioretinal atrophy if (1) the areas of atrophy were not...

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Identifiers

PMID: 33838313
DOI: 10.1016/j.oret.2021.03.016
PMCID: PMC8497635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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