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Article

Probability of consolidation constrains novel serotype emergence in dengue fever virus.

PloS one - 1 Jan 2021

Sánchez-González Gilberto, Belak Zachery R, Lozano Luis, Condé Renaud

Abstract excerpt

Since their first sequencing 40 years ago, Dengue virus (DENV) genotypes have shown extreme coherence regarding the serotype class they encode. Considering that DENV is a ribonucleic acid (RNA) virus with a high mutation rate, this behavior is intriguing. Here, we explore the effect of various parameters on likelihood of new serotype emergence. In order to determine the time scales of such an event, we used a...

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Identifiers

PMID: 33819302
DOI: 10.1371/journal.pone.0248765
PMCID: PMC8021166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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