Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia.

doi:10.1038/s41467-020-18997-2

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Article

Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia.

Nature communications - 19 Oct 2020

Moreau Clara A, Urchs Sebastian G W, Kuldeep Kumar, Orban Pierre, Schramm Catherine, Dumas Guillaume, Labbe Aurélie, Huguet Guillaume, Douard Elise, Quirion Pierre-Olivier, Lin Amy, Kushan Leila, Grot Stephanie, Luck David, Mendrek Adrianna, Potvin Stephane, Stip Emmanuel, Bourgeron Thomas, Evans Alan C, Bearden Carrie E, Bellec Pierre, Jacquemont Sebastien

Abstract excerpt

16p11.2 and 22q11.2 Copy Number Variants (CNVs) confer high risk for Autism Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder (ADHD), but their impact on functional connectivity (FC) remains unclear. Here we report an analysis of resting-state FC using magnetic resonance imaging data from 101 CNV carriers, 755 individuals with idiopathic ASD, SZ, or ADHD and 1,072 controls....

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Identifiers

PMID: 33077750
DOI: 10.1038/s41467-020-18997-2
PMCID: PMC7573583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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