Article
Radiomics Biomarkers Correlate with CD8 Expression and Predict Immune Signatures in Melanoma Patients.
Molecular cancer research : MCR - 1 Jun 2021
Aoude Lauren G, Wong Bernadette Z Y, Bonazzi Vanessa F, Brosda Sandra, Walters Shaun B, Koufariotis Lambros T, Naeini Marjan M, Pearson John V, Oey Harald, Patel Kalpana, Bradford Julia J, Bloxham Conor J, Atkinson Victoria, Law Phillip, Strutton Geoffrey, Bayley Gerard, Yang Samuel, Smithers B Mark, Waddell Nicola, Miles Kenneth, Barbour Andrew P
Abstract excerpt
Treatment for metastatic melanoma includes targeted and/or immunotherapy. Although many patients respond, only a subset has complete response. As late-stage patients often have multiple tumors in difficult access sites, non-invasive techniques are necessary for the development of predictive/prognostic biomarkers. PET/CT scans from 52 patients with stage III/IV melanoma were assessed and CT image parameters were...
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