Article
The Interaction of Human and Epstein-Barr Virus miRNAs with Multiple Sclerosis Risk Loci.
International journal of molecular sciences - 13 Mar 2021
Afrasiabi Ali, Fewings Nicole L, Schibeci Stephen D, Keane Jeremy T, Booth David R, Parnell Grant P, Swaminathan Sanjay
Abstract excerpt
Although the causes of Multiple Sclerosis (MS) still remain largely unknown, multiple lines of evidence suggest that Epstein-Barr virus (EBV) infection may contribute to the development of MS. Here, we aimed to identify the potential contribution of EBV-encoded and host cellular miRNAs to MS pathogenesis. We identified differentially expressed host miRNAs in EBV infected B cells (LCLs) and putative host/EBV miRNA...
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